Steven Joffe, MD, MPH, is the Emanuel and Robert Hart Professor of Medical Ethics and Health Policy at the University of Pennsylvania Perelman School of Medicine. He serves as Chief of the Division of Medical Ethics, and directs the Penn Fellowship in Advanced Biomedical Ethics and the Penn Postdoctoral Training Program in the Ethical, Legal and Social Implications (ELSI) of Genetics and Genomics. He is also Professor of Pediatrics at the Perelman School of Medicine. Dr. Joffe attended Harvard College, received his medical degree from the University of California at San Francisco (UCSF), and received his public health degree from UC Berkeley. He trained in pediatrics at UCSF and undertook fellowship training in pediatric hematology/oncology at the Dana-Farber Cancer Institute and Boston Children’s Hospital. His clinical work is in the area of stem cell transplantation in children. His research addresses the many ethical challenges that arise in the conduct of clinical and translational investigation, both in pediatric oncology and other areas of medicine and science. He has been the principal investigator (PI) of studies that examine the roles and responsibilities of PIs in multicenter randomized trials, accountability in the clinical research enterprise, return of individual genetic results to participants in epidemiologic cohort studies, the integration of genomic sequencing technologies into the clinical care of cancer patients, and governance of learning activities in learning healthcare systems. He currently serves as a member of the U.S. Food and Drug Administration’s (FDA) Pediatrics Ethics Subcommittee, a member of the National Institutes of Health Clinical Center’s Board of Scientific Governors, and as a member of the National Human Genome Research Institute’s Genomics and Society Working Group.